NDM-1, OXA-48 and OXA-181 carbapenemase-producing Enterobacteriaceae in Sultanate of Oman

347Antimicrobial Susceptibility of OXA-48, NDM-1 And VIM-4 Carbapenemase-producing Clinical Isolates of Enterobacteriaceae From Kuwait Government Hospitals

347. Antimicrobial Susceptibility of OXA-48, NDM-1 And VIM-4 Carbapenemase-producing Clinical Isolates of Enterobacteriaceae From Kuwait Government Hospitals Wafaa Jamal, MD, PhD, FRCPath; John Albert, PhD; Laurent Poirel, PhD; Vincent Rotimi, MD, PhD, FRCPath; Microbiology, Faculty of Medicine, Kuwait University, Safat, Kuwait; Medical and Molecular Microbiology, Faculty of Science, University...

Evaluation of a new phenotypic OXA-48 disk test for differentiation of OXA-48 carbapenemase-producing Enterobacteriaceae clinical isolates.

The current phenotypic methods for detecting carbapenemase-producing Enterobacteriaceae (CPE) allow differentiation between class A and B carbapenemases, but they cannot confirm in a single test class D OXA-48 carbapenemase producers. In this study, we evaluated a new phenotypic test, the OXA-48 disk test, which is based on an imipenem disk and two blank disks adjacent to the imipenem disk, loa...

Emergence of OXA-48-producing Enterobacteriaceae in Switzerland.

Genome sequence of OXA-48 carbapenemase-producing Klebsiella pneumoniae KpO3210.

Klebsiella pneumoniae KpO3210 is a OXA-48 carbapenemase-producing isolate obtained from a blood culture in the context of an outbreak in Hospital Universitario La Paz (Madrid, Spain) in 2010. It belongs to the major clone detected during the outbreak and is resistant to all beta-lactams and to several other antibiotics.

Comparative evaluation of a novel chromogenic medium (chromID OXA-48) for detection of OXA-48 producing Enterobacteriaceae.

Comparative evaluation of the recently developed chromogenic culture medium chromID OXA-48 (bioMérieux) with chromID CARBA (bioMérieux) and SUPERCARBA showed that chromID OXA-48 and SUPERCARBA media have the highest sensitivity for detection of OXA-48 producing Enterobacteriaceae (91% and 93%) comparatively to chromID CARBA (21 %). The chromID OXA-48 has the highest specificity, with 100%, as c...